SAN DIEGO (WISH) — Men have condoms and vasectomies as birth control options, but researchers this week presented data on a protein that could be part of a non-hormonal pill for men.
Some birth control pills for men are in development but have possible side effects of weight gain, depression and increased cholesterol, says A press release on the search for the non-hormonal pill. The pills being developed also affect testosterone, the statement said.
Gunda Georg, head of the Department of Medicinal Chemistry at the University of Minnesota, and Md Abdullah Al Noman, a graduate student in his lab, presented an overview of their research on YouTube at the American Chemical Society Spring Meeting.
They said the protein they found would bind to a form of vitamin A to make men temporarily infertile without any obvious side effects.
Mice given the protein became sterile after four weeks, the researchers said. Once they stopped giving the mice the protein, they became fertile again after two weeks. Trials in mice were 99% effective.
The pill containing the protein is expected to enter clinical trials as early as the end of 2022, the researchers said. Federal approval of the pills, however, is taking time and could mean the pills won’t be available until 2027.
The researchers received support and funding from the National Institutes of Health and the Male Contraceptive Initiative.